SUPPORT

Translation of a Bismuth-Gadolinium Nanoparticle for MR-guided Radiation Therapy

2020-2025
NIH 1R01CA240804
Role: PI
Major Goals: To develop and test a novel Bi-Gd nanoparticle for use in MR-guided radiation therapy.

A Novel Flat-panel Detector for Advanced On-board Radiation Therapy Imaging

2014-2025
NIH 1R01CA188446
Role: PI
Major Goals: To design, build and test a new detector for beam’s-eye-view imaging during lung cancer radiation therapy.

CaNCURE: Cancer Nanomedicine Co-ops for Undergraduate Research Experiences

2014-2024
NIH 1R25CA174650
Role: Mentor (PI: Sridhar)
Major Goals: To train the next generation of scientists, technologists and physicians skilled in research at the interface of nanotechnology, biology and medicine.

Nanobody Immune-guided Radiation Therapy

2020-2023
ViewRay, Inc.
Role: Co-PI (Co-PI Schoenfeld)
Major Goals: To develop and test nanobodies conjugated to MRI-contrast nanoparticles for imaging immune receptor status in vivo.

Master Research Agreement

2013-2023
Varian Medical Systems, Inc.
Role: PI
Major Goals: This agreement funds multiple projects in clinical medical physics.

A Surface Chemistry Guided Approach to the Rational Design of Low-energy Electron Emitting Nanomaterials

2020-2021
NIH 1R56EB027683
Role: Subcontract PI (PI: Sykes and Mace)
Major Goals: To design and test novel nanoparticles for radiotherapy applications

Gold Nanoparticles as Vascular Disrupting Agents in Radiation Therapy of NSCLC

2015-2018
NIH 1R21CA188833
Role: PI
Major Goals: To study tumor blood vessel disruption during radiation therapy in combination with targeted gold nanoparticles in a lung tumor model.

Enhancing tumor vascular damage with gold nanoparticles aided radiation therapy

2012-2014
NIH 1R03CA164645
Role: PI
Major Goals: To study the mechanism of action in gold nanoparticle aided radiotherapy.

Lung Sparing for SBRT with beam’s-eye-view images and real time tumor tracking

2011-2014
NIH 1R21CA156068
Role: PI
Major Goals: To develop a real-time lung tumor tracking system.

• JCRT Foundation
• Brigham Research Institute
• Kaye Scholar Award
• Varian Medical Systems, Inc.